Kyle Shanahan told NBC Sports Bay Area’s Greg Papa on “49ers Game Plan" that rookie running back Isaac Guerendo could be set ...

The recent retirement of Aaron Donald, the three-time Defensive Player of the Year and a key figure in the Rams' defense, has ...

Suddenly in doubt for the Week 3 game at L.A. are tight end George Kittle, defensive end Nick Bosa, and cornerback Charvarius ...

Los Angeles Rams offensive coordinator Mike LaFleur mentioned that having quarterback Jimmy Garoppolo in the locker room ...

Head coach Kyle Shanahan detailed the 49ers latest injury updates headed into the team's first NFC West matchup vs. the Los ...

Head coach Kyle Shanahan shared the final injury report ahead of the 49ers Week 3 matchup and discussed the team's ...

Kyle Shanahan is considered one of the smartest offensive coaches in the NFL, but according to former NFL coach Jay Gruden, ...

Bang Bang, Niner Gang! From award-winning SF Chronicle journalist Mike Silver comes the inside story of the brilliant, ...

San Francisco 49ers head coach Kyle Shanahan candidly reveals impact of not facing Los Angeles Rams defensive tackle Aaron ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

Brandon Aiyuk caught four passes for 43 yards in the San Francisco 49ers' Week 2 loss to the Minnesota Vikings. While it may ...